Dr. Peter J. D'Adamo, MD
About the Book
For more than 25 years, Dr. Peter J. D'Adamo has been extensively researching the connections between blood type, food, and disease. Combining his findings with previously established research by other scientists in his field, Dr. D'Adamo published his first book, Eat Right 4 Your Type, in 1996. It became a New York Times bestseller and brought worldwide recognition to Dr. D'Adamo's blood-type theories. NutriBooks named it one of the ten most influential health books ever written.
The Next Evolution In Dieting
Dr. D'Adamo's blood-type theories contributed to his ongoing research on genetics and nutrition and led to the publication of The GenoType Diet in 2008. Based on the powerful conclusion that individuals have the ability to alter their genes' behavior, The GenoType Diet takes the science behind the Blood Type Diet a significant step further. Dr. D'Adamo's statistical analyses of the clustering together of genes, disorders, and physical traits produced six distinct and durable categories: the six GenoTypes.
"D'Adamo's engaging writing style, enthusiasm for his subject and personalized advice will appeal to those who enjoy taking a hands-on approach to their health and exploring new theories."
THE GENOTYPE DIET
by Dr. Peter J. D'Adamo
The excerpt below is from the revolutionary new book, The GenoType Diet, by Dr. Peter J. D'Adamo, author of the blockbuster bestseller, "Eat Right 4 Your Type."
Dr. D'Adamo helped millions of people achieve better health through eating properly for their blood type. In The GenoType Diet, his work takes an evolutionary leap. Based on years of research into human genetics, The GenoType Diet is a sophisticated approach to healthy eating and weight loss based on six common genetic profiles.
Through statistical analyses of how genes, disorders, and physical traits were known to cluster together, Dr. D'Adamo concluded that we all fit into one of the following GenoTypes: The Hunter, The Gatherer, The Teacher, The Explorer, The Warrior, and The Nomad. He didn't make up these profiles -- they naturally surface through analysis. The six "GenoTypes" derive from genetically-encoded survival strategies that cause some people to hoard fat, others to be allergic to grains, others to have trouble digesting dairy products, and so on.
The science behind gene stimulation and retardation is called "methylation" -- coating genes through diet to make them harder or easier to express. The excerpt explains how methylation works and how it relates to human nutrition.
You'll find more information about the book, The GenoType Diet, and author Peter J. D'Adamo, after the excerpt. Thanks for considering this material.
"Change your Genetic Destiny"
by Dr. Peter J. D'Adamo
Over three decades ago, I was a typically mixed-up teenager attending a highly regarded Catholic high school. During sophomore year, we had the good fortune to have the wizened Father Kenney as our religion teacher. His lectures were always well attended, perhaps as the result of his policy of allowing students to smoke cigarettes in class.
Between long puffs of his own, followed by streaming eruptions of grayish-blue smoke, Father Kenney would hold forth on the universe.
"Father Kenney, why do bad things happen to good people?" "Well, because God so values free choice, he is willing to let events, both good and bad, unfold."
"How can you accept science and evolution and still believe in God?"
Long inhale. Slow exhale.
"Because there is nothing so small, or so elemental, that you cannot see the hand of God in it."
Now, a lot of evolutionary scientists are atheists. I happen not to be one of them. However, the problem with mixing religion and science is that you are trying to reconcile certainty and uncertainty, and if you are certain about something, your thoughts about it can't grow very much.
Genetics is intimately linked with evolution and natural selection. When genes reproduce, the process occasionally screws up and a mistake, or "mutation" occurs. Most mutations are bad, but every once in a while, a mutation occurs that alters the odds of that species surviving. If it is a big enough improvement, it enters the gene pool and perhaps a new species is born.
Theoretically, this all happens in a random (if somewhat heartless) manner and over a very long time. Talking about genes is always a bit risky -- many people admit to being concerned or scared by the whole thing and perhaps wish that geneticists would just leave well enough alone. However, genetics is rich with possibilities despite the fact that what is revealed often challenges long-accepted ideas and notions.
When I was five years old, I was stricken with a bad case of the measles. To help lift my spirits up, my parents brought home a new toy. It was a terrarium type of tank to which you added a special powder and water. Over the next few days, my listlessness and apathy turned to wonder as brightly colored stalactites materialized and grew ever higher, Each morning upon awakening, I would rush to my desk across the room to marvel at what magic had happened while I was asleep.
But what would have been the response if my parents had just given me a premade stalactite garden? I can tell you. About two minutes of attention and then relegation to the closet. What was fascinating about the toy was its *process*, not its *outcome.* If we assume that events which fascinate God are similar to the types of things that fascinate a little boy, then it is possible to have faith and also live in a fact-based world.
Epigenetics takes the evolution discussion to the next level. Rather than worrying about whether you came from an amoeba or some small mammal that made a wrong turn, you can worry about things much more relevant -- like whether the weaknesses introduced into your heredity from grandparents and parents will come home to roost within you.
More important, you can do more than just worry -- you can do something about it. By putting The GenoType Diet to work, not only do you make choices that will change your destiny, but under the right conditions they'll go on to change the destiny of your descendents.
There is a famous story about a rabbi and a young child. The rabbi was planting a plum tree sapling. Like most kids, this one was direct and to the point. "Isn't it kind of stupid to plant a tiny sapling when at your age there is no chance that you will be alive to ever taste those plums?" said the child. The rabbi thought a minute and answered the child's question with one of his own.
"Do you like plums?"
Hopefully, you get the point. There is a future somewhere out there. If we care to, we can live in the present and let the future take care of itself. However, for those of us with the ambition and who are ready to do the work, epigenetics holds the promise of an improvable future of health for us and those who come after us.
What if I told you that in four generations you and your immediate descendants could change the epigenetic patterns of inheritance in your family line and eliminate diabetes, heart disease, and some forms of cancer? We all know a family of long-lived people or a family where nobody seems to get cancer but everyone worries about getting Alzheimer's disease, which seems to strike half of all the family members. These are epigenetic traits within those families. Carried over several generations, they imprint themselves into the family's epigenome as well. That's why we see so much attention deficit disorder(ADD), obesity, high blood pressure, cancer, and diabetes in our modern population.
If we can imprint bad stuff through lack of attention or ignorance, can we, with knowledge, just as easily imprint good things as well? Your grandchildren could be the first to parent this new generation of epigenetically healthy children. All it takes is guts, vision and a plan.
That's what the GenoType Diet is all about.
~ ON METHYLATION ~
Brown-eyed genes have three chances out of four to prevail. Why do those genes "speak louder" than the blue-eyed ones? The answer lies in a process called "methylation," whereby sections of the allele for blue eyed genes are coated by molecules called methyl groups, causing the section of DNA on which they reside to wind up tightly.
Winding up DNA prevents it from being read, essentially turning it off. Methylation is one of the ways that nature silences the messages of certain genes. This coating process blocks the DNA at the site of that gene from being "read," and since reading DNA is critical to the gene's ability to express itself, the gene is silenced.
Major amounts of methylation happen at the moment of conception, at about eight weeks into the embryo's development and about a month before birth. After that, it's pretty much downhill; as we age, our DNA gradually loses methyl groups. So far, we can't control what happens at conception: We don't yet know how to make sure that my eyes are brown instead of blue. But research has shown that we can encourage the proper methylation of certain genes *after* conception, primarily through diet.
The right diet can help remethylate all sorts of genes that we want to keep quiet, including the thrifty genes that program our cells to store every single extra calorie as fat, or the reactive genes that cause us to have an asthma attack in a dusty room, or the tolerant genes that make us susceptible to one cold after another.
~ ON HISTONE ACETYLATION ~
The second major epigenetic process is known as "histone acetylation." "Histones" are spool-like molecules that cause DNA to wind into dense coils. That's important, because if you stretched out one of your DNA strands, you'd discover that it was six feet long (albeit microscopically thin). Histones are like little spools that allow your DNA to fit inside your cells as it winds around them.
Now, when DNA is all coiled up like that, it can't be read. So any DNA that's coiled around a histone has basically been silenced. It may be part of your genetic code, but it isn't going to be the loudest part.
Of course we need our DNA to speak some of the time; otherwise, our cells couldn't reproduce. Our body gets DNA to unwind by placing molecules called "acetyl groups" onto the histones. These acetyl groups unwind the DNA -- and it speaks. Then, when it needs to be wound back up and silenced, enzymes remove the acetyl group and the DNA spools around your histones once again.
Actually, the process is a bit more intricate than that. Whenever your DNA is wound up on its little histones, one small portion of it still is available for reading, even though most of it is silenced. So if you imagine all the trillions of cells within your body, each with its own DNA, tiny portions of your DNA are available for reading in each cell. The trick, as with methylation, is to try to get the "right" portions of the DNA to be read while keeping the "wrong" parts wound up on their spools.
This process is controlled by two enzymes. One enzyme gets our DNA to unwind, the other gets that same DNA to curl up around its histones. As you've probably guessed by now, the levels of these enzymes are affected by your prenatal experience, environment, diet, and lifestyle. Moreover, many of the same foods and supplements that encouraged the right kind of methylation encourage the right kind of histone acetylation as well. So that's another way that your GenoType Diet can affect which of your genes speaks and which are silent.
Like genes, histones can also be methylated. As a matter of fact, it is thought that the more permanently silenced alleles (like the blue-eye allele from my dad) are actually silenced by turning off their histones, and binding them up for good.
Copyright ©2008 by Epigenetic Archetypes, LLC. From the book "The Genotype Diet," by Dr. Peter J. D'Adamo with Catherine Whitney, published by Broadway Books, a division of Random House, Inc. Reprinted with permission.
Named Physician of the Year in 1990 by the American Association of Naturopathic Physicians, Dr. Peter J. D'Adamo currently serves as the academic dean for the Institute for Human Individuality (IFHI).
In 1999, respected industry analysts named Dr. D'Adamo's book, Eat Right 4 Your Type one of the Ten Most Influential Health Books of the Century. Dr. Peter D'Adamo the was recognized as "Most Intriguing Health Author of 1999."
The Journal of Alternative and Complementary Medicine hailed Eat Right 4 Your Type as the "boldest of the new books on Alternative Medicine." An international phenomenon, the series Eat Right 4 Your Type, Cook Right 4 Your Type, and Live Right 4 Your Type has been translated into more than 50 languages worldwide.
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